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| UNC's Aziz Sancar on a Turkish postage stamp |
The Nobel Prize web site has great, clear explanations of the important discoveries that have been recognized with the award, along with the key experiments that led to these discoveries. The newest ones have both introductory and advanced explanations as pdf files.
The Nobel Prizes are announced each October. Most of the ones below were awarded for discoveries that we're discussing in class.
- 1974: George Palade and the secretory process
- 1986: Cell-cell signaling by growth factors
1992: Reversible protein phosphorylation as a biological switch
location to get your selfie! - 1997: Certain proteins (prions) can act as infectious agents
- 1999: Discovery of signal sequences for protein sorting
- 2001: The cell cycle
- 2007: Oliver Smithies at UNC! (Oliver passed away in 2017, but his spouse – also a scientist – uses his old Nobel parking space on campus).
- 2008: GFP
- 2012: G protein-coupled receptors in cell communication
- 2014: Super-resolution microscopy
- 2015: UNC's Aziz Sancar for DNA repair mechanisms! Go Heels!
- 2017: CryoEM
- 2020: CRISPR
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| Charpentier and Doudna, from a great video about their work on CRISPR and their 2020 Nobel Prize. |